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May 1, 1989˜The œNew York times book review134 citations

Viral and bacterial infections in patients with acute myocardial infarction

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KMKimmo Mattila

Structured PICO

Are viral and bacterial infections associated with acute myocardial infarction in males aged 50 years or less?

P
Population
111 males aged 50 years or less, comprising 40 consecutive patients with acute myocardial infarction, 41 random controls, and 30 patients with chronic coronary heart disease.
I
Intervention
Viral and bacterial infections (assessed via antibody titers and history of recent influenza-like illness)
C
Comparator
Random controls and patients with chronic coronary heart disease
O
Outcome
Occurrence of viral and bacterial infections (rise in antibodies or recent influenza-like illness)

Recent enterobacterial infections and influenza-like illnesses are significantly associated with acute myocardial infarction in young men.

Abstract

Abstract. The association of both viral and bacterial infections with acute myocardial infarction was investigated in a case‐control study involving 40 consecutive patients with an acute myocardial infarction, 41 random controls and 30 patients with chronic coronary heart disease. All individuals were males aged 50 years or less. A rise in enterobacterial common antigen antibodies (15/40) and a recent influenza‐like illness (11/40) were significantly more common among patients with acute myocardial infarction compared with the other groups. No differences were observed between the groups in the occurrence of antibodies against eight other bacterial antigens or 16 viruses.

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Cite This Study

Kimmo Mattila (1989) studied this question.

synapsesocial.com/papers/6a11e551997792fb8c8e0feehttps://doi.org/10.1111/j.1365-2796.1989.tb00084.x
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