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A valid method for determining the carboxyhemoglobin level in the body has been developed. The method is based on the 20-second breath-holding method. Our work shows that a polyvinyl bag can be used for collection of samples in the field. An application of this method is reported. This confirms the fact that cigarette smoking is a major factor in determining the carboxyhemoglobin level in a population. Pipe and cigar smokers appear not to have much increase in carboxyhemoglobin. The method should be suitable for studying the relationship of carboxyhemoglobin to occupational and to ambient air pollution exposures. 11 references, 7 figures, 4 tables.
Ringold et al. (Mon,) studied this question.
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