Why the study?
Does 3-dimensional echocardiography accurately reflect invasive hemodynamic changes in patients with pulmonary hypertension?
Population
23 consecutive Japanese patients with pulmonary hypertension, mean age 55.3, 19 females / 4 males…
Design
Cross-sectional, Hemodynamic data were obtained by cardiologists independently…
Key result
3-dimensional echocardiography-derived diastolic and systolic remodeling indices significantly correlated with pulmonary vascular resistance (R=0.67, P=0.0005 and R=0.55, P=0.006, respectively).
Authors
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Hypothesis-generating for non-invasive PVR surrogates in PH; leaves open prospective validation before clinical use.
Observational (n=23)
Does 3-dimensional echocardiography accurately reflect invasive hemodynamic changes in patients with pulmonary hypertension?
Effect estimate: R=0.67
p-value: p=0.0005
Novel 3D echocardiography indices, particularly the diastolic remodeling index (RVEDVI/LVEDVI), strongly correlate with invasive pulmonary vascular resistance and may serve as non-invasive indicators of hemodynamic severity in pulmonary hypertension.
Inaba et al. (2012) conducted an observational in Pulmonary hypertension (n=23). 3-dimensional echocardiography vs. Cardiac magnetic resonance imaging and right heart catheterization was evaluated on Correlation of diastolic remodeling index (RVEDVI/LVEDVI) with pulmonary vascular resistance (R=0.67, p=0.0005). 3-dimensional echocardiography-derived diastolic and systolic remodeling indices significantly correlated with pulmonary vascular resistance (R=0.67, P=0.0005 and R=0.55, P=0.006, respectively).