Left atrial appendage closure using the LAmbre device achieved 100% successful sealing at 3 months in patients with nonvalvular atrial fibrillation, regardless of prior catheter ablation.
Cohort (n=17)
Is left atrial appendage closure using the LAmbre device feasible and safe in patients with nonvalvular atrial fibrillation, regardless of prior catheter ablation status?
Left atrial appendage closure using the LAmbre device is feasible, safe, and achieves high sealing rates in patients with nonvalvular atrial fibrillation, regardless of whether they have had prior catheter ablation.
Absolute Event Rate: 100% vs 100%
p-value: p=>0.05
Left atrial appendage (LAA) closure (LAAC) has emerged as an alternative therapeutic approach to medical therapy for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF). However, complex LAA anatomy may preclude its use. LAmbre is a new, self-expanding LAA occluder, and is highly adaptable to different LAA morphologies. We explored the feasibility, safety, and efficacy of LAAC using LAmbre device in NVAF patients with or without prior catheter ablation (CA). LAAC using LAmbre device was applied in NVAF patients with (group C) or without (group N) prior CA. Transesophageal echocardiography (TEE) was performed at 3, and 12 months post-LAAC. Among 17 LAAC patients (group C, 6 six patients (35.3%) had residual flow 0.05). LAAC with LAmbre device, subsequent to prior CA for AF, can be performed successfully and safely. The design and distinguishing features of this device could be of help in patients with complex anatomy of LAA.
Feng et al. (Mon,) conducted a cohort in Nonvalvular Atrial Fibrillation (n=17). Left atrial appendage closure using the LAmbre device vs. Patients without prior catheter ablation was evaluated on Successful sealing of the left atrial appendage (p=>0.05). Left atrial appendage closure using the LAmbre device achieved 100% successful sealing at 3 months in patients with nonvalvular atrial fibrillation, regardless of prior catheter ablation.