What question did this study set out to answer?

The aim is to explore the efficiency of DNA immobilization and delivery using polyethylenimine-grafted multiwalled carbon nanotubes.

July 1, 2005

Polyethylenimine‐Grafted Multiwalled Carbon Nanotubes for Secure Noncovalent Immobilization and Efficient Delivery of DNA

Key Points

The aim is to explore the efficiency of DNA immobilization and delivery using polyethylenimine-grafted multiwalled carbon nanotubes.
DNA is immobilized onto multiwalled carbon nanotubes via electrostatic interactions with grafted polyethylenimine.
Transfection efficiency is compared to that of pure polyethylenimine.
The polyethylenimine-grafted multiwalled carbon nanotubes achieve DNA delivery efficiency similar to or higher than pure PEI.

Abstract

DNA hits the wall: DNA is immobilized securely onto the surface of multiwalled carbon nanotubes through electrostatic interactions with grafted polyethylenimine (PEI; see picture). The polyethylenimine-graft multiwalled carbon nanotubes carrying DNA show transfection efficiency for DNA delivery similar to or even several times higher than PEI.

Polyethylenimine‐Grafted Multiwalled Carbon Nanotubes for Secure Noncovalent Immobilization and Efficient Delivery of DNA

Key Points

Abstract

Cite This Study

Also Consider

Also Consider