Among hypertensive patients, urban residence (HR 2.12), proteinuria (HR 1.87), and diabetes mellitus (HR 1.70) were identified as major risk factors for developing cardiovascular disease.
Cohort (n=343)
No
Proteinuria, diabetes mellitus, and urban residence are significant risk factors for cardiovascular disease in hypertensive patients.
BACKGROUND: Cardiovascular diseases are a group of disorders of the heart and blood vessels. Globally an estimated 17.9 million people died from cardiovascular diseases, which covers 31% of all global deaths, and the three quarters taking place in developing countries. Hypertension is the major cause of cardiovascular diseases. Its influence is high with other risk factors. This study aimed to determine the major risk factors of cardiovascular disease among hypertensive patients at Jimma University Medical Center. METHODS: Using December to January 2017 hypertension-related report of Jimma University Medical Center (JUMC), a retrospective cohort study type was conducted on purposively selected 343 patients. Three nurses from JUMC participated in the data collection, and the data were fitted using the Cox-Proportional Hazard (Cox-PH) model. RESULTS: About 138 (40.23%) patients were experienced cardiovascular disease at 28 months median time. From the Cox-PH model, the hazard ratio and 95% CI of age (HR = 1.0495, 95% CI: 1.0250-1.0747), urban (HR = 2.1225, 95% CI: 1.3813-3.2613), diabetes mellitus (HR = 1.702, 95% CI: 1.0082-2.8731), proteinuria (HR = 1.8749, 95% CI: 1.2675-2.7734), two drug users (HR = 0.2533, 95% CI: 0.1376-0.4662), systolic blood pressure (HR = 1.0343, 95% CI: 1.0147-1.0542) and pulse rate (HR = 1.0111, 95% CI: 0.9933-1.0293). CONCLUSION: The presence of proteinuria, diabetes mellitus, and being an urban resident had a great impact on the cardiovascular diseases of hypertensive patients.
Ayele et al. (Sat,) conducted a cohort in Hypertension (n=343). Risk factors (urban residence, diabetes mellitus, proteinuria) was evaluated on Cardiovascular disease. Among hypertensive patients, urban residence (HR 2.12), proteinuria (HR 1.87), and diabetes mellitus (HR 1.70) were identified as major risk factors for developing cardiovascular disease.