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PROGRESS in chemotherapy of systemic mycoses has been sufficiently slow to recall the lament of Ecclesiastes: "The thing that hath been, it is that which shall be; and that which is done is that which shall be done; and there is no new thing under the sun." Comparison of this review with another published in the Journal in 19631 may reinforce such a conviction. Still, something remains to be said for broadening our knowledge of old drugs and gleaning what one can about newer agents.Polyene AntibioticsThis large group of antibiotics includes three drugs commercially available in this country: . . .
John E. Bennett (1974) studied this question.