Mutations of Bacterial Viruses Affecting Their Host Range

Key Points

• The study aims to explore the relationship between mutations in bacterial viruses and their ability to infect phage-resistant bacteria.
• Analyzed mutations of bacterial viruses that resulted in changes in host range
• Compared resistant bacterial forms and corresponding viral adaptations
• Followed up on earlier work regarding phage-resistant bacteria from 1943.
• Demonstrated that bacteria can mutate to resist certain phages
• Showed that phages can similarly mutate to successfully infect these resistant bacteria