Treatment with the novel antiviral pocapavir in a neonate with enterovirus myocarditis resulted in significant left ventricular remodeling, although dystrophic calcification persisted.
Case Report (n=1)
Dystrophic myocardial calcification occurs in the setting of myocardial injury and normal serum calcium. We present a case of a neonate with prominent dystrophic calcification and severe left ventricular systolic dysfunction in the setting of enterovirus myocarditis. These findings are superbly illustrated by multiple imaging modalities. The patient was treated with the novel antiviral, pocapavir, in addition to a standard heart failure regimen. The dystrophic calcification persisted but the left ventricle remodeled significantly. To our knowledge, this is the first reported use of pocapavir for this indication. The literature regarding enterovirus myocarditis and pocapavir is briefly reviewed.
Wittekind et al. (Sat,) conducted a case report in Enterovirus myocarditis with severe dystrophic calcification (n=1). Pocapavir was evaluated on Left ventricular remodeling and dystrophic calcification. Treatment with the novel antiviral pocapavir in a neonate with enterovirus myocarditis resulted in significant left ventricular remodeling, although dystrophic calcification persisted.
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