November 23, 2011

Expanding the Azaspiro3.3heptane Family: Synthesis of Novel Highly Functionalized Building Blocks

Key Points

Key points are not available for this paper at this time.

Abstract

The preparation of versatile azaspiro3.3heptanes carrying multiple exit vectors is disclosed. Expedient synthetic routes enable the straightforward access to these novel modules that are expected to have significance in drug discovery and design.

Perguntar à IA

Bookmark

Cite This Study

Burkhard et al. (Wed,) studied this question.

synapsesocial.com/papers/6a1916b06298e9f701be3aec https://doi.org/https://doi.org/10.1021/ol2028459

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Computer-based de novo design of drug-like molecules2005 · 968 citations
2Oxetanes. IX. Structural and Solvent Effects in the Reaction of γ-Bromoalcohols with Base<sup>1,2</sup>1959 · 45 citations
3An asymmetric approach to 5-O-carbamoyl-2-epi-polyoxamic acid and the total synthesis of 2′′-epi-polyoxin J2009 · 13 citations
4Azetidines and bisazetidines. Their synthesis and use as the key intermediates to enantiomerically pure diamines, amino alcohols, and polyamines1991 · 107 citations
5Oxetanes in Drug Discovery: Structural and Synthetic Insights2010 · 405 citations

Perguntar à IA

Bookmark