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The development of gene transfer vectors from lentiviruses, such as the human immunodeficiency virus 1 (HIV-1), has opened exciting perspectives for the genetic treatment of a wide array of inherited and acquired diseases, because of their ability to achieve the efficient delivery, integration, and long-term expression of transgenes into dividing and nondividing cells both in vitro and in vivo.
Follenzi et al. (Fri,) studied this question.