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LACUNES may be defined as ischemic infarcts of restricted size in the deeper parts of the brain. Absent from the cerebral and cerebellar cortex, they are best known in the chronic healed stage when they form irregular cavities, 0.5 to 15 mm. in diameter, principally in the basal ganglia and basis pontis (Figs. 1, 2, 3,
C. Miller Fisher (Sun,) studied this question.