GLP-1 Receptor Agonists in the Male Aesthetic Practice: Opportunities for the Dermatologic Surgeon

BACKGROUND AND OBJECTIVES The demand for male aesthetic treatments continues to rise, and with increased utilization of the glucagon-like peptide-1 receptor agonists (GLP-1RAs), we anticipate a growing need to address these concerns. This narrative review examined the intersection of skin-related effects of GLP-1RAs and male aesthetics, focusing on the role of the dermatologic surgeon in their management. METHODS A search of the available peer-reviewed literature through March 2026 in the PubMed database was conducted. Search terms included combinations of terms related to GLP-1RAs, male aesthetics, and dermatologic treatments. Studies were included if they were peer-reviewed, published in English, and relevant to the topic. RESULTS Many concerns that drive men to seek aesthetic treatments overlap with secondary cutaneous manifestations of GLP-1RA treatments including hair loss, changes in facial and body volume, and skin quality and laxity. Management options include, but are not limited to, dermal fillers for volume restoration and biostimulatory agents for skin laxity, along with medical and procedural interventions for hair loss. CONCLUSION Dermatologic surgeons are well-positioned to address GLP-1 receptor agonist-related aesthetic concerns in male patients. Practitioners should be prepared to offer evidence-based, customized treatment strategies as this population grows.