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Transmural pressure significantly determines systemic vascular resistance even above critical closing pressures, while an active venous-arteriolar reflex mechanism limits these resistance changes when venous transmural pressure varies. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

January 1, 1956Open Access

The Relation of a Venous-Arteriolar Reflex to Transmural Pressure and Resistance in Small and Large Systemic Vessels

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Abstract

Data are presented which indicate that, even in pressure ranges well above critical closing pressures, transmural pressure is an important factor in determining systemic vascular resistance but that a mechanism is present which actively limits these pressure changes in resistance when transmural pressure is varied on the venous side.

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Haddy et al. (Sun,) studied this question.

synapsesocial.com/papers/6a1be446c97d63156a5f119e https://doi.org/https://doi.org/10.1161/01.res.4.1.25

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5Critical Closing Pressure and Venous Pressure1952 · 38 citations

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