The atherogenic index of plasma was significantly associated with obstructive coronary artery disease in patients with stable angina pectoris (OR 3.74; 95% CI 1.62-8.64; p=0.020).
Observational (n=345)
Does the atherogenic index of plasma predict obstructive coronary artery disease in patients with stable angina pectoris?
The atherogenic index of plasma is a significant predictor of obstructive coronary artery disease in patients with stable angina pectoris, with a cut-off value of 0.49 indicating ≥50% stenosis.
Effect estimate: OR 3.74 (95% CI 1.62-8.64)
p-value: p=0.020
Aims: Chronic coronary syndrome is associated with several risk factors, such as dyslipidemia and hypertension. The atherogenic index of plasma (AIP) has been demonstrated to be a biochemical risk factor for coronary artery disease (CAD). This study aimed to determine whether the AIP is an effective parameter for estimating obstructive CAD. Methods and Results: A total of 345 patients (with a mean age of 62.2 ± 10.3; 63% male) who underwent coronary angiography were included in this study. Obstructive CAD is defined as having one or more vessels with a stenosis level of ≥50%. Depending on the presence of obstructive CAD, all patients were divided into two groups. The mean AIP value was found to be 0.538 ± 0.26 in the study group. The AIP values were significantly higher in the obstructive coronary artery group (AIP; 0.49 ± 0.26 vs. 0.58 ± 0.27, p = 0.002). According to a univariable analysis, AIP values were significantly associated with obstructive coronary artery disease OR: 3.74 (CI 95% 1.62–8.64), p = 0.020. The AIP was further adjusted for confounding risk factors in three multivariable analysis models and, all three models showed a significant association. According to an ROC analysis, 0.49 is the cut-off value for AIP, and a value above 0.49 indicates 50% coronary artpery stenosis. Conclusions: The AIP may be used in the assessment of cardiovascular risk for patients with stable angina pectoris, and it may also be used to estimate obstructive CAD.
Kürklü et al. (Thu,) conducted a observational in Stable Angina Pectoris (n=345). Atherogenic index of plasma (AIP) was evaluated on Obstructive coronary artery disease (≥50% stenosis) (OR 3.74, 95% CI 1.62-8.64, p=0.020). The atherogenic index of plasma was significantly associated with obstructive coronary artery disease in patients with stable angina pectoris (OR 3.74; 95% CI 1.62-8.64; p=0.020).
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