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The effects of combining fosfomycin with various antimicrobial agents were evaluated in vitro by broth microdilution checkerboard and time-kill kinetic studies. Checkerboard analyses were used to evaluate the following 30 Gram-negative isolates: 5 Pseudomonas aeruginosa , 5 Acinetobacter baumannii - Acinetobacter calcoaceticus species complex, and 20 Enterobacteriaceae isolates.
Flamm et al. (Tue,) studied this question.
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