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Background: Aging of the myocardium is a dynamic process which involves progressive loss of cardiomyocytes due to necrosis and apoptosis, interstitial fibrosis and reactive hypertrophy of the remaining vital cardiomyocytes. In our study, we investigated the postnatal changes in the myocardium of 15 adult male Wistar rats, distributed in the following age groups: 2 weeks, 1, 3, 6 and 12 months old. We used routine hematoxylin and eosin staining and Mallory’s trichrome stain.
Kotov et al. (Fri,) studied this question.