September 10, 2020Open Access

Discovery of Covalent Inhibitors Targeting the Transcriptional Enhanced Associate Domain Central Pocket

HKHacer KarataşWest Virginia University MAMohammad AkbarzadehRazi University HAHélène AdihouEuropean Organisation for Rare Diseases

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Abstract

values, and reduce TEAD target gene expression. This methodology promises to enable new medicinal chemistry programs aimed at the modulation of TEAD activity.

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synapsesocial.com/papers/6a1da408a25575e2d9ce205b https://doi.org/https://doi.org/10.1021/acs.jmedchem.0c01275

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