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Basic principles of fluid dynamics and material properties underlie many facets of the diagnosis, treatment, and natural history of vascular disease. I review the concepts of total fluid energy and both viscous and inertial energy losses with reference to arterial occlusive disease. I contrast the vascular wall properties of arteries and veins and discuss the relevance of mechanical principles to arterial aneurysm. I review the pathophysiologic features of small and large arteriovenous fistula. Finally, I discuss the altered dynamics associated with venous obstruction and valvular insufficiency in light of recent noninvasive diagnostic techniques that provide simple rapid assessment of venous pathophysiologic features.
Robert W. Barnes (Fri,) studied this question.
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