Cardiac myxoma is an uncommon benign mesenchymal neoplasm of the heart characterized by specific immunohistochemical markers and treated with prompt surgical excision.
Cardiac myxomas are benign mesenchymal neoplasms with distinct immunohistochemical profiles that require prompt surgical excision due to embolization risk.
Cardiac myxoma is an uncommon benign mesenchymal neoplasm of the heart. It usually arises in the left atrium, near the valve of the fossa ovalis, and most frequently affects adults in the third through the sixth decades of life. It is hypothesized to arise from subendothelial vasoformative reserve cells or primitive cells that differentiate along the lines of the endothelium, but this remains speculative. Microscopically, the neoplastic cells are arranged individually, and nests, and are oriented in single or multiple layers around vascular channels. The neoplastic cells are immunoreactive for vimentin, calretinin, S100, nonspecific enolase, factor VIII, CD31, and CD34. The tumor can have diverse clinical presentations depending on its location and extent of disease and is predisposed to embolization. The current treatment is prompt surgical excision.
Torres et al. (Thu,) conducted a review in Cardiac myxoma. Cardiac myxoma is an uncommon benign mesenchymal neoplasm of the heart characterized by specific immunohistochemical markers and treated with prompt surgical excision.