Does the presence of metabolic syndrome increase carotid intima media thickness compared to controls without metabolic syndrome?
Patients with metabolic syndrome have significantly increased carotid intima-media thickness compared to healthy controls, indicating a higher burden of subclinical atherosclerosis.
BACKGROUND B-mode measurement of the thickness of wall of major arteries now possible. We wanted to measure the Carotid Intima Media Thickness (CIMT) assess its correlation in subjects of Metabolic Syndrome (MS). is a case control study conducted among 200 participants in Acharya Vinoba Rural Tertiary Care Hospital in central India. 100 patients with metabolic and 100 without metabolic syndrome fulfilling the inclusion and criteria were included in the study. Anthropometric measurements height, weight, waist circumference, and BMI were recorded. Blood was measured by standard methods. CIMT was measured by B-mode as per protocol. age of the subjects in metabolic syndrome group and non-metabolic group was 44. 93 ± 15. 34 and 37. 72 ± 12. 83 respectively. 85% of the with metabolic syndrome were obese (BMI ≥ 25 Kg/M 2). Triglycerides were higher (>150 mg/dL) in 66% of metabolic syndrome subjects as to control group (10%). The mean CIMT in MS group was 0. 81 ± 0. 23 in control group was (0. 66 ± 0. 13) ; the difference was statistically significant (p<0. 005). subjects have increased CIMT that predisposes them to future cardiovascular.
Sethia et al. (Mon,) studied this question.