Vitreous Opacities Diagnostic of Familial Primary Amyloidosis

IN 1953 Kantarjian and DeJong1 first described the A presence of vitreous opacities in a family with amyloidosis. Subsequently, Rukavina and his coworkers2 reported cases with vitreous opacities in another family, and Falls et al.3 suggested that the morphology of the opacities, especially when they occurred in the absence of signs of intraocular inflammation, might be of diagnostic aid. In 1958 the vitreous opacities occurring in a case of familial primary amyloidosis were proved to consist of amyloid.4 This indicated that the distinctive appearance of these deposits was indeed pathognomonic of the disease.Primary amyloidosis ranks with disseminated lupus erythematosus, . . .