A Multiple-Domain Model using machine learning classified 56 countershocks for defibrillation success with an average accuracy of 83.9% and an ROC area under the curve of 81.4%.
Observational (n=56)
Does a multiple-domain machine learning model accurately predict defibrillation success in patients with ventricular fibrillation during cardiac arrest?
A novel machine learning model using time-series and wavelet features can predict defibrillation success with high accuracy, potentially guiding real-time clinical decisions during cardiac arrest.
Effect estimate: AUC 81.4%
Ventricular Fibrillation(VF) waveform can represent rapidly worsening chances of defibrillation success, and those of subsequent Return of Spontaneous Circulation (ROSC), during a cardiac arrest. We propose a new method to analyze the chaotic nature of VF using multiple feature extraction and machine learning techniques. Human cardiac arrest data was acquired from the Richmond Ambulance Authority. A Multiple-Domain Model (MDM), which utilizes time-series and wavelet features, was developed. We report two new time-series features that are predictive of countershock (CS) success. Support vector machines were used with a radial basis function to classify 56 CS, 21 successful and 35 unsuccessful, with an average accuracy of 83.9%. Sensitivity and specificity were 71.4% and 91.4%, respectively. ROC area under the curve of 81.4% was achieved. The proposed predictive model performs real-time, short-term analysis of ECG, through signal-processing and machine-learning techniques, and can be accurate enough for clinical application. As more cardiac arrest data is acquired, improved MDM performance is anticipated.
Shandilya et al. (Sun,) conducted a observational in Cardiac arrest with Ventricular Fibrillation (n=56). Multiple-Domain Model (MDM) using machine learning was evaluated on Countershock success classification (AUC 81.4%). A Multiple-Domain Model using machine learning classified 56 countershocks for defibrillation success with an average accuracy of 83.9% and an ROC area under the curve of 81.4%.
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