High-sensitivity cardiac troponin T was an independent predictor of prehypertension (OR 1.043; 95% CI 1.019-1.067; P<0.001).
Case-Control (n=100)
Does high-sensitivity cardiac troponin T (hs-cTnT) level predict prehypertension in adult subjects?
High-sensitivity cardiac troponin T levels are significantly elevated in prehypertensive patients and may serve as a biomarker for predicting prehypertension.
Odds Ratio: 1.043 (95% CI 1.019–1.067)
p-value: p=<0.001
BACKGROUND: High-sensitivity cardiac troponin T (hs-cTNT) is an important non-invasive laboratory-based marker of subclinical myocardial injury. Prehypertension, which may be a precursor of hypertension, is a major public health issue. Our aim was to evaluate the importance of serum hs-cTnT as a marker predicting prehypertension. METHODS: A total of 100 subjects (45 women and 55 men) consisting of 50 consecutive prehypertensive patients with blood pressures between 120/80 and 139/89 mmHg and 50 normotensive patients with blood pressures < 120/80 mmHg were enrolled prospectively. The hs-cTNT level was calculated and compared between the two groups. Echocardiographic examinations were performed in all patients. RESULTS: The hs-cTnT level was significantly higher in the prehypertensive group (p < 0.001) and was positively correlated with prehypertension (r = 0.625, p < 0.001). Hs-cTnT was an independent predictor of prehypertension (odds ratio = 1.043, 95% confidence interval CI 1.019-1.067, p < 0.001). An Hs-cTnT level of 0.55 ng/L was predictive of prehypertension with a sensitivity of 86% and specificity of 60% (area under the curve = 0.861; 95% CI, 0.787-0.935; p < 0.001). CONCLUSION: hs-cTnT may complement other diagnostic biomarkers in predicting prehypertension. Abbrevations: high-sensitivity cardiac troponin T, prehypertension, subclinical myocardial injury.
Aşkın et al. (Wed,) conducted a case-control in Prehypertension (n=100). High-sensitivity cardiac troponin T (hs-cTnT) vs. Normotensive patients was evaluated on Prehypertension (OR 1.043, 95% CI 1.019-1.067, p=<0.001). High-sensitivity cardiac troponin T was an independent predictor of prehypertension (OR 1.043; 95% CI 1.019-1.067; P<0.001).