Low load resistance training with blood flow restriction increased peak reactive hyperemia (1,400 to 1,716 ml/min; P=0.047) and transiently improved popliteal FMD% (P=0.002).
Does low load resistance training with blood flow restriction improve regional vascular adaptation in healthy males?
Low load resistance training with blood flow restriction induces early and transient vascular adaptations at the conduit, resistance, and capillary levels.
Absolute Event Rate: 1716% vs 1400%
p-value: p=0.047
Distortion to hemodynamic and ischemic stimuli during blood flow restriction (BFR) exercise may influence regional vascular adaptation. We examined changes at the conduit, resistance, and capillary level in response to low load resistance exercise with BFR. Eleven males (22 ± 3 yr, 178 ± 4 cm, 78 ± 9 kg) completed 6 wk (3 days/wk) unilateral plantar flexion training with BFR at 30% 1 repetition maximum (1-RM). The contralateral leg acted as a nonexercised control (CON). Popliteal artery function flow-mediated dilation, FMD% and structure maximal diameter and resistance vessel structure peak reactive hyperemia were assessed using Doppler ultrasound before and at 2-wk intervals. Calf filtration capacity was assessed using venous occlusion plethysmography before and after training. BFR training elicited an early increase in peak reactive hyperemia (1,400 ± 278 vs. 1,716 ± 362 ml/min at 0 vs. 2 wk; t-test: P = 0.047), a transient improvement in popliteal FMD% (5.0 ± 2.1, 7.6 ± 2.9, 6.6 ± 2.1, 5.7 ± 1.6% at 0, 2, 4 and 6 wk, respectively; ANOVA: P = 0.002), and an increase in maximum diameter (6.06 ± 0.44 vs. 6.26 ± 0.39 mm at 0 vs. 6 wk; Bonferroni t-test: P = 0.048). Capillary filtration increased after 6 wk BFR training (P = 0.043). No changes in the CON leg were observed. Adaptation occurred at all levels of the vascular tree in response to low load resistance exercise with BFR. Enhanced peak reactive hyperemia and transient improvement in popliteal artery function occurred before changes in artery structural capacity.
Hunt et al. (Fri,) reported a other. Low load resistance training with blood flow restriction vs. Contralateral nonexercised control leg was evaluated on Peak reactive hyperemia at 2 weeks (p=0.047). Low load resistance training with blood flow restriction increased peak reactive hyperemia (1,400 to 1,716 ml/min; P=0.047) and transiently improved popliteal FMD% (P=0.002).
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