Negative affectivity significantly predicted worse metabolic control (path coefficient 0.29 for HbA1c) and lower quality of life across all domains in patients with Type 2 diabetes.
Cross-Sectional (n=261)
No
Does Negative Affectivity worsen Quality of Life and metabolic control in patients with Type 2 Diabetes Mellitus?
Negative affectivity is a significant psychological vulnerability factor that negatively impacts both quality of life and glycemic control in patients with Type 2 Diabetes.
Effect estimate: Path coefficient 0.29
p-value: p=<0.01
Introduction: It is essential to consider the clinical assessment of psychological aspects in patients with Diabetes Mellitus (DM), in order to prevent potentially adverse self-management care behaviors leading to diabetes-related complications, including declining levels of Quality of Life (QoL) and negative metabolic control. Purpose: In the framework of Structural Equation Modeling (SEM), the specific aim of this study is to evaluate the influence of distressed personality factors as Negative Affectivity (NA) and Social Inhibition (SI) on diabetes-related clinical variables (i.e., QoL and glycemic control). Methods: The total sample consists of a clinical sample, including 159 outpatients with Type 2 Diabetes Mellitus (T2DM), and a control group composed of 102 healthy respondents. All participants completed the following self- rating scales: The Type D Scale (DS14) and the World Health Organization QoL Scale (WHOQOLBREF). Furthermore, the participants of the clinical group were assessed for HbA1c, disease duration and BMI. The observed covariates were BMI, gender, and disease duration, while HbA1c was considered an observed variable. Results: SEM analysis revealed significant differences between groups in regards to the latent construct of NA and the Environmental dimension of QoL. For the clinical sample, SEM showed that NA had a negative impact on both QoL dimensions and metabolic control. Conclusions: Clinical interventions aiming to improve medication adherence in patients with T2DM should include the psychological evaluation of Type D Personality traits, by focusing especially on its component of NA as a significant risk factor leading to negative health outcomes.
Conti et al. (Wed,) conducted a cross-sectional in Type 2 Diabetes Mellitus (n=261). Negative Affectivity vs. Lower Negative Affectivity / Healthy controls was evaluated on Metabolic control (HbA1c) (Path coefficient 0.29, p=<0.01). Negative affectivity significantly predicted worse metabolic control (path coefficient 0.29 for HbA1c) and lower quality of life across all domains in patients with Type 2 diabetes.