The virus neutralization test (VNT) is currently the most appropriate diagnostic test to detect antibodies specific to sheep pox, goat pox, and lumpy skin disease virus. There is one commercial enzyme-linked immunosorbent assay (ELISA) available; however, this ELISA has some limitations. Several antigens have been identified as possible targets but have not been compared and assessed with the virus neutralization test and commercial ELISA. Improving serological testing for capripoxviruses is required to improve control of capripoxviruses and to demonstrate freedom from infection.
Teffera et al. (Fri,) studied this question.