ABSTRACT Transcranial direct current stimulation (tDCS) is an emerging neuromodulation technique that has garnered significant attention for its potential in modulating brain activity and treating various neurological and psychiatric conditions. This narrative review provides a comprehensive overview of the mechanisms underlying tDCS, diverse clinical applications of tDCS, including its use in stroke rehabilitation, treatment-resistant depression, cognitive enhancement, and other neurological and psychiatric disorders. While the therapeutic potential of tDCS is promising, we also address the challenges associated with its application, such as methodological variability, individual differences in response and ethical considerations. Furthermore, we discuss the limitations of current research and suggest directions for future studies. As tDCS continues to evolve, it holds the potential to revolutionize neurorehabilitation and cognitive enhancement, offering new avenues for both clinical practice and research in neuroscience.
Panda et al. (Fri,) studied this question.
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