This article reviews the RADIOSOUND-HTN trial comparing three renal denervation treatment arms for resistant hypertension, discussing conclusions and open questions for future studies.
Do different technologies and techniques for catheter-based renal denervation have different effects on blood pressure in patients with resistant hypertension?
This article reviews the RADIOSOUND-HTN trial, which compared different renal denervation devices and techniques for treating resistant hypertension.
The interest in renal denervation (RDN) as a treatment for arterial hypertension has returned with three proof of principle trials that have shown recently RDN to be superior to sham treatment. Nevertheless, many questions about this treatment remain open, including those around the optimal interventional technique and technology. To clarify this important question, the authors designed and conducted the Randomized Trial of Different Renal Denervation Devices and Techniques in Patients with Resistant Hypertension (RADIOSOUND-HTN) trial, which compared three RDN treatment arms in a prospective randomised clinical trial. In this article, they comment on the background and results of this trial, and discuss which conclusions can be drawn from the trial, and which questions remain open for future studies in this field.
Lurz et al. (Mon,) conducted a review in Resistant Hypertension. Renal denervation (RDN) vs. Different RDN treatment arms was evaluated. This article reviews the RADIOSOUND-HTN trial comparing three renal denervation treatment arms for resistant hypertension, discussing conclusions and open questions for future studies.