Transcatheter mitral valve repair with MitraClip demonstrated a 97% success rate and 7% 30-day MACE rate, with increased experience reducing procedure time, hospital stay, and MACE.
Observational (n=75)
No
Does increased institutional experience with transcatheter mitral valve repair (MitraClip) improve procedural and clinical outcomes in patients with primary mitral regurgitation?
The learning curve for TMVR with MitraClip demonstrates that while initial procedural success is high, increased institutional experience significantly reduces procedure time, fluoroscopy time, hospital stay, and complications.
OBJECTIVES: This study sought to assess the learning curve for TMVR for treatment of primary mitral regurgitation (MR). BACKGROUND: Data are lacking regarding the technical experience required to achieve optimal clinical outcomes with transcatheter mitral valve repair (TMVR) using the edge-to-edge MitraClip technique. METHODS: We examined the sequential experience of the first 75 patients (age 80 ± 9 years; 77% male) who underwent TMVR at our institution. A sequence number of each patient was assigned as a continuous variable and in tertiles for analysis. RESULTS: TMVR with MitraClip was successful in 97% with an average procedural time of 106 ± 39 minutes. The 30-day rate of major adverse cardiovascular events was 7%. With increased case experience, there were decreases in procedural time, fluoroscopy time, length of hospital stay, and major adverse cardiovascular events. Procedural success, residual mitral regurgitation and NYHA functional classification at 30-day follow-up remained unchanged throughout the experience. CONCLUSIONS: The learning curve for TMVR with MitraClip for treatment of primary MR is characterized by a sequential reduction in procedure time, fluoroscopy time, procedural complications, and hospital length of stay at a tertiary academic medical center. Thirty-day procedural results are favorable and similar during the initial learning period.
Eleid et al. (2016) conducted an observational in Primary mitral regurgitation (n=75). Transcatheter mitral valve repair (TMVR) with MitraClip was evaluated on Procedural success, procedural time, and 30-day major adverse cardiovascular events. Transcatheter mitral valve repair with MitraClip demonstrated a 97% success rate and 7% 30-day MACE rate, with increased experience reducing procedure time, hospital stay, and MACE.