Six independent predictors of mortality in adult patients receiving ECMO were identified: age, stroke, need for dialysis, pre-ECMO infection, hypoglycemia, and alkalosis.
Observational (n=607)
No
What are the independent predictors of mortality in adult patients receiving ECMO as mechanical circulatory support?
In adult patients receiving ECMO for mechanical circulatory support, age, stroke, need for dialysis, pre-ECMO infection, hypoglycemia, and alkalosis are independent predictors of mortality.
Extracorporeal membrane oxygenation (ECMO) is a resource-consuming and highly invasive treatment. There were 1100 ECMO cases at the National Taiwan University Hospital between August 1994 and November 2008. Of these, 607 were adults (>18 years old) who received ECMO as mechanical circulatory support. In this study, patient characteristics and complications during the ECMO course were evaluated for their correlation with prognosis. The following factors were significantly different between survivors and nonsurvivors: age, coronary artery disease, diabetes mellitus, brain death, stroke during ECMO, the need for dialysis during ECMO, pre-ECMO infection, hypoglycemia, acidosis, alkalosis, the need for a distal perfusion catheter, and the amount of red blood cells transfused. Six independent predictors of mortality were identified: age, stroke, the need for dialysis during ECMO, pre-ECMO infection, hypoglycemia, and alkalosis. Our institution has comparatively extensive experience with adult patients, which may be quite different from other medical centers with respect to distribution of patient age. The findings should lead to better utilization of ECMO for adult patients in the future.
Lan et al. (Mon,) conducted a observational in Patients requiring mechanical circulatory support (n=607). Patient characteristics and complications during ECMO vs. Survivors vs nonsurvivors was evaluated on Mortality (prognosis). Six independent predictors of mortality in adult patients receiving ECMO were identified: age, stroke, need for dialysis, pre-ECMO infection, hypoglycemia, and alkalosis.