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September 1, 1996Synlett79 citations

A Novel, Stereocontrolled Synthesis of 1,2-trans-Cyclopropanes: Cyclopropyl Boronate Esters as Partners in Suzuki Couplings with Aryl Halides

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JHJens P. HildebrandEvonik (Germany)SMStephen P. MarsdenUniversity of Leeds

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Abstract

All articles of this category A novel, stereospecific synthesis of 1,2- trans -disubstituted cyclopropanes is described, based upon the palladium (0) mediated cross-coupling of cyclopropyl boronic esters with aryl halides. This work forms the basis of a proposed new asymmetric synthesis of cyclopropanes. cyclopropane - palladium - Suzuki - cyclopropyl boronate

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Hildebrand et al. (1996) studied this question.

synapsesocial.com/papers/6a7170b487f9210571283a95https://doi.org/10.1055/s-1996-5608
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