Laryngoscopic endotracheal intubation produced statistically significant differences in haemodynamic responses compared to laryngeal mask airway insertion (P<0.05).
RCT (n=100)
Randomly divided
Does laryngeal mask airway insertion reduce haemodynamic pressor responses compared to laryngoscopic endotracheal intubation in adult hypertensive patients undergoing elective surgery?
Laryngeal mask airway insertion is associated with a significantly lower haemodynamic pressor response compared to endotracheal intubation in hypertensive patients undergoing general anaesthesia.
p-value: p=<0.05
INTRODUCTION: Laryngoscopy and endotracheal intubation has been the mainstay in providing adequate airway management, delivering general anaesthesia but are associated with hypertension, tachycardia and arrhythmias. These haemodynamic responses may be more hazardous in hypertensive patients. OBJECTIVE: In this study, we aimed to compare the haemodynamic response elicited by laryngoscopic endotracheal intubation with laryngeal mask airway insertion, in ASA II of adult hypertensive patients. METHODS: The study conducted on 100 hypertensive patients of either sex aged between 20 and 60 years belonging to ASA II grade and scheduled for elective surgery. The patients were randomly divided into two groups of 50 patients each. In one group (Group I) laryngoscopic endotracheal intubation was done and in another group (Group II) laryngeal mask airway was inserted. Baseline vitals of the patients (SBP, DBP, MAP, HR, SpO2) were documented. Patients were given inj. Midazolam 2mg IM and Phenargan 25 mg IM as premedication before the elective surgery. General anaesthesia was administered. Haemodynamics including heart rate, blood pressure and SpO2 were recorded every minute till intubation or insertion and at 1,3,5 minutes after intubation or insertion and then every 5 minutes till 20 minutes. RESULTS: All the haemodynamic responses (SBP,DBP,MAP,HR) in Laryngoscopy + Endotracheal Intubation Group compared to the Laryngeal Mask Airway Insertion Group was statistically signicant as the p value is <0.05. CONCLUSION: The laryngeal mask airway may be used for airway management during anaesthesia in hypertensive patients on treatment in whom the pressor response would be deleterious.
Kumari et al. (2022) conducted an RCT in Hypertension (n=100). Laryngoscopic endotracheal intubation vs. Laryngeal mask airway insertion was evaluated on Haemodynamic responses (SBP, DBP, MAP, HR) (p=<0.05). Laryngoscopic endotracheal intubation produced statistically significant differences in haemodynamic responses compared to laryngeal mask airway insertion (P<0.05).