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July 21, 2025Insects27 citationsOpen Access

The Role of Heat Shock Proteins in Insect Stress Response, Immunity, and Climate Adaptation

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DBDavide BanfiTBTommaso BianchiMMMaristella Mastore

Key Points

  • Heat shock proteins are crucial for insect resilience to biotic and abiotic stresses including temperature changes and pathogens.
  • They stabilize cellular proteins, interact with antioxidant systems, and support the innate immune response in insects.
  • HSP expression reflects evolutionary adaptation, helping insects cope with diverse environmental challenges.
  • Investigating HSP interactions with stress response systems could enhance our understanding of ecological adaptation under climate change.

Abstract

Heat shock proteins (HSPs) play a key role in enhancing insect resilience to abiotic and biotic stresses by preserving cellular integrity and modulating immune responses. This review summarizes the main functions of HSPs in insects, including protein stabilization, interaction with antioxidant systems, and involvement in the innate immune response. The expression of HSPs under environmental conditions reflects their evolutionary adaptation to various stressors, including thermal changes, chemical exposure, and pathogens. Future research should focus on the interaction between HSPs and other stress response systems to improve our understanding of insect adaptation. Furthermore, in the context of global climate change, HSPs emerge as a crucial resilience factor and potential biomarkers for environmental monitoring.

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Cite This Study

Banfi et al. (2025) studied this question.

synapsesocial.com/papers/689a060ee6551bb0af8cd35fhttps://doi.org/10.3390/insects16070741
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