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July 23, 20250 citations

Endoscopic transnasal resection of clival meningiomas. Systematic literature review and analysis of surgical outcomes in 20 patients

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ASA N ShkaruboICI V ChernovAVA A Veselkov

Key Points

  • Endoscopic transnasal approaches for clival meningiomas show varied resection outcomes, with 10% achieving complete resection.
  • Literature review included 21 studies covering 43 patients, highlighting the surgical complexity of clival meningiomas.
  • In our study, partial resection occurred in 55% of cases, reflecting challenges in complete tumor removal.
  • Complication rates were low, indicating the endoscopic approach is a viable option in neurosurgery for these tumors.

Abstract

Abstract Introduction Treatment of clival meningiomas remains one of the unresolved problems in contemporary neurosurgery. Studies on this topic are rare, and the objective of our research is to evaluate the current outcomes of endoscopic transnasal approaches in the surgical management of meningiomas of the clival region. Objective of the Study To conduct a systematic analysis of literature dedicated to endoscopic transnasal surgery of clival meningiomas. To analyze the surgical outcomes in our series of patients with clival meningiomas. Materials and Methods Our study included 20 patients with clival meningiomas. Tumor resection was performed using an endoscopic transnasal transsphenoidal transcavernous (posterior extended) approach. A literature search was conducted using the Medline database (via PubMed) and Google Scholar. In total, 21 articles were included in the analysis, encompassing treatment of 43 patients. Results In our series, complete resection was achieved in 2 cases (10%), near-total resection in 3 cases (15%), subtotal resection in 4 cases (20%), and partial resection in 11 cases (55%). According to the aforementioned classification of the extent of tumor resection, complete tumor removal was achieved in 18.6% of cases, near-total removal in 6.3%, subtotal removal in 39%, and partial removal in 26.6% of cases. In the remaining 9.5% of cases, the extent of resection was not specified. The complication rate was not high. Conclusions Considering the difficult location of these tumors, the endoscopic transnasal approach serves as an additional option alongside transcranial approaches in the planning of surgical treatment.

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Cite This Study

Shkarubo et al. (2025) studied this question.

synapsesocial.com/papers/689a0621e6551bb0af8cde33https://doi.org/10.21203/rs.3.rs-7106604/v1
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