Autonomous vehicles (AVs) hold the potential to revolutionize transportation by improving safety, operational efficiency, and environmental impact. However, ensuring reliability and safety in real-world conditions remains a major challenge. Based on an in-depth examination of 33 peer-reviewed studies (2015–2025), this systematic review organizes advancements across five key domains: fault detection and diagnosis (FDD), collision avoidance and decision making, system reliability and resilience, validation and verification (V&V), and safety evaluation. It integrates both hardware- and software-level perspectives, with a focus on emerging techniques such as Bayesian behavior prediction, uncertainty-aware control, and set-based fault detection to enhance operational robustness. Despite these advances, this review identifies persistent challenges, including limited cross-layer fault modeling, lack of formal verification for learning-based components, and the scarcity of scenario-driven validation datasets. To address these gaps, this paper proposes future directions such as verifiable machine learning, unified fault propagation models, digital twin-based reliability frameworks, and cyber-physical threat modeling. This review offers a comprehensive reference for developing certifiable, context-aware, and fail-operational autonomous driving systems, contributing to the broader goal of ensuring safe and trustworthy AV deployment.
Mahmood et al. (2025) studied this question.