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Synapse
August 2, 20250 citations

Figure S6 from Single-Cell Analysis of Posttranslational Modifications Identifies Immunosuppressive Macrophage Subtypes in the HBV-Positive Hepatocellular Carcinoma Microenvironment

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HZHuakan ZhaoRRRan RenXZXi Zhang

Key Points

  • Single-cell analysis reveals distinct immunosuppressive macrophage subtypes within hepatocellular carcinoma.
  • The tumor microenvironment (TME) differs significantly between high-risk and low-risk cases based on IMC data.
  • Identifying macrophage subtypes helps understand their roles in HBV-positive liver cancer progression.
  • These findings highlight the importance of macrophage behavior in developing targeted therapies for hepatocellular carcinoma.

Abstract

Comparison of the TME of HR and LR using IMC data.

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Cite This Study

Zhao et al. (2025) studied this question.

synapsesocial.com/papers/689a0c72e6551bb0af8d01b9https://doi.org/10.1158/2326-6066.29760553
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