Seminal plasma from bulls with divergent plane of nutrition minimally alters bovine uterine endometrial epithelial cell gene expression in vitro

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Analysis demonstrates distinct gene expression changes in endometrial epithelial cells from cattle based on seminal plasma and nutritional status.

Seminal plasma alters the transcriptome of bovine endometrial epithelial cells, with significant effects detected.
A total of 7,905 differentially expressed genes were identified in cells treated with seminal plasma from high gain bulls compared to control.
Observational analysis of gene expression utilized RNA sequencing and statistical modeling to compare treatment effects across groups.
Though seminal plasma impacts gene expression, the nutritional plane showed only minimal effects on the overall transcriptome changes.

Swanson et al. (2025) studied this question.

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View Full Paper

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Analysis demonstrates distinct gene expression changes in endometrial epithelial cells from cattle based on seminal plasma and nutritional status.

Seminal plasma alters the transcriptome of bovine endometrial epithelial cells, with significant effects detected.
A total of 7,905 differentially expressed genes were identified in cells treated with seminal plasma from high gain bulls compared to control.
Observational analysis of gene expression utilized RNA sequencing and statistical modeling to compare treatment effects across groups.
Though seminal plasma impacts gene expression, the nutritional plane showed only minimal effects on the overall transcriptome changes.

Swanson et al. (2025) studied this question.

View Full Paper

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