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August 16, 2025Open Access

The Quest for Non-Invasive Diagnosis: A Review of Liquid Biopsy in Glioblastoma

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Authors

MEMaria George EliasHHHarry HadjiyiannisFVFatemeh Vafaee

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Overview

This review explores liquid biopsy’s role in glioblastoma diagnosis, highlighting biomarkers and AI's impact.

Key Points

  • Liquid biopsy offers a non-invasive alternative for assessing glioblastoma biomarkers, improving diagnostic accuracy and monitoring.
  • Blood and cerebrospinal fluid are analyzed for circulating tumour DNA and other biomarkers, aiding in treatment decisions and prognosis.
  • Assessment focuses on recent advancements and challenges in liquid biopsy applications, emphasizing the need for standardized methodologies.
  • While promising, liquid biopsy implementation for glioblastoma faces hurdles like low biomarker levels and requires further research and validation.

Cite This Study

Elias et al. (2025) studied this question.

synapsesocial.com/papers/68a366a20a429f797332c73fhttps://doi.org/10.20944/preprints202508.0558.v1
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