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August 21, 2025Eurosurveillance2 citationsOpen Access

Two diphtheria sub-clusters with autochthonous cases in Germany and Poland within a Corynebacterium diphtheriae ST-574 outbreak, 2022 to July 2025

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IPImme Friederike Roewer de PortoADAlexandra DangelLSLothar Schneider

Key Points

  • Two sub-clusters identified in a Corynebacterium diphtheriae outbreak, with many cases acquired locally rather than through travel.
  • Among 27 cases, there were 16 cutaneous cases and 5 respiratory cases, highlighting a public health concern.
  • Observational analysis across multiple regions showed that 12 affected individuals had experienced homelessness, complicating the outbreak.
  • Strengthened immunisation and international surveillance are crucial, as implications of migration-associated cases are significant.

Abstract

Within a Corynebacterium diphtheriae ST-574 outbreak comprising mostly migration-associated cases since 2022, Germany detected two sub-clusters in 2025. Among sub-cluster cases with travel information (24/26), 22 were acquired autochthonously. One of two imported cases came from a Polish voivodeship having an additional case. Sub-cluster 1 included 16 cutaneous cases, sub-cluster 2 included six cutaneous and five respiratory cases. One unvaccinated child and two older adults died. Of 27 cases, 12 experienced homelessness. Strengthened immunisation, improved wound care and international surveillance are needed.

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Cite This Study

Porto et al. (2025) studied this question.

synapsesocial.com/papers/68af541fad7bf08b1eadbac3https://doi.org/10.2807/1560-7917.es.2025.30.33.2500539
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