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August 24, 2025Nanomaterials13 citationsOpen Access

Multimodal Fusion-Driven Pesticide Residue Detection: Principles, Applications, and Emerging Trends

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MWMei WangZLZ B LiuFYFulin Yang

Key Points

  • Chromatography-mass spectrometry provides the highest accuracy for detecting pesticide residues, ensuring food safety.
  • Emerging technologies, including nano-enhanced sensors, improve sensitivity and efficiency in pesticide detection.
  • Biosensors enable real-time detection in the field, offering a portable alternative to traditional lab methods.
  • Ongoing challenges in cost and complexity highlight the need for innovative solutions in pesticide residue detection.

Abstract

Pesticides are essential for modern agriculture but leave harmful residues that threaten human health and ecosystems. This paper reviews key pesticide detection technologies, including chromatography and mass spectrometry, spectroscopic methods, biosensing (aptamer/enzyme sensors), and emerging technologies (nanomaterials, AI). Chromatography-mass spectrometry remains the gold standard for lab-based precision, while spectroscopic techniques enable non-destructive, multi-component analysis. Biosensors offer portable, real-time field detection with high specificity. Emerging innovations, such as nano-enhanced sensors and AI-driven data analysis, are improving sensitivity and efficiency. Despite progress, challenges persist in sensitivity, cost, and operational complexity. Future research should focus on biomimetic materials for specificity, femtogram-level nano-enhanced detection, microfluidic “sample-to-result” systems, and cost-effective smart manufacturing. Addressing these gaps will strengthen food safety from farm to table while protecting ecological balance. This overview aids researchers in method selection, supports regulatory optimization, and evaluates sustainable pest control strategies.

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Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/68af5bc7ad7bf08b1eae018ehttps://doi.org/10.3390/nano15171305
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