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August 23, 2025Computation0 citationsOpen Access

Optimal Control Strategies for a Mathematical Model of Pneumonia Infection

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NANaif B. AlmutairiMEMoustafa El-Shahed

Key Points

  • Reduction in pneumonia infections achieved through targeted control strategies, enhancing public health response.
  • The basic reproduction number R0 is crucial for determining stability: R0 < 1 ensures disease-free equilibrium, while R0 > 1 indicates endemic stability.
  • Assessment using a mathematical model illustrates the dynamics of pneumonia infection and interventions to mitigate it.
  • Pneumonia control measures may enable effective public health interventions, suggesting strategic awareness and treatment campaigns.

Abstract

In this study, we formulate and analyze a deterministic mathematical model describing the transmission dynamics of pneumonia. A comprehensive stability analysis is conducted for both the disease-free and endemic equilibrium points. The disease-free equilibrium is locally and globally asymptotically stable when the basic reproduction number R0 1. To evaluate effective intervention strategies, an optimal control problem is formulated by introducing time-dependent control variables representing awareness campaigns, screening of carriers, and treatment of infected individuals. Applying Pontryagin’s Maximum Principle, the simulation results confirm the effectiveness of the proposed control strategies in reducing the number of infections and mitigating the overall disease burden. The findings offer valuable insights into the control of pneumonia and highlight the potential impact of strategic public health interventions.

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Cite This Study

Almutairi et al. (2025) studied this question.

synapsesocial.com/papers/68af5bc7ad7bf08b1eae01a6https://doi.org/10.3390/computation13090204
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