Congenital lobar emphysema (CLE), also referred to as congenital alveolar overdistension, is characterized by hyperinflation in one or more pulmonary lobes. This condition is a developmental anomaly affecting the lower respiratory tract. Commonly present in the neonatal period, cases beyond the first month of life may pose a diagnostic challenge due to non-specific symptoms. We are reporting a 45-day thriving male infant presented to the Outdoor clinic with the complaint of bringing up feed and at times fast breathing without respiratory distress for the 1 week.
A 2025 study studied this question.