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September 10, 2025European Journal of Cancer Care1 citationsOpen Access

Cancer Cachexia in Clinical Practice: A Review of Treatment Barriers Among Cancer Patients

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NANaema AlamawiAAAnas AlsharawnehHAHasan Abualruz

Key Points

  • Barriers to cancer cachexia management include knowledge gaps among patients and healthcare professionals.
  • About 20% of cancer deaths are attributed to cancer cachexia, highlighting its impact on patient outcomes.
  • The literature review utilized various electronic databases to identify studies on cancer cachexia barriers.
  • Understanding and addressing both modifiable and nonmodifiable barriers is crucial for effective management.

Abstract

Background: Cancer cachexia is a multifactorial syndrome that affects patients’ quality of life and survival. It accounts for over 20% of cancer deaths. Despite its high incidence, there is no evidence‐based standard of care for managing it. Early detection and management require preventative measures and multimodal therapy. Aim: The purpose of this study was to conduct an in‐depth review of the literature on cancer cachexia and its barriers for effective assessment and management. Methods: The literature review was conducted through various electronic databases to identify studies published on cancer cachexia and its barriers for effective assessment and management of cancer cachexia. Results: The review indicated that barriers for effective assessment and management of cancer cachexia were on three levels: patients, health workers, and organizations. Also, there is a knowledge gap in understanding, assessing, and managing cancer cachexia among healthcare workers, patients, and family members. Conclusion: The research indicates that patients, family members, and healthcare professionals lack sufficient knowledge about how to identify, assess, and treat cancer cachexia. This gap has a lot of important barriers, both modifiable and nonmodifiable. Patients, healthcare professionals, and organizations are the three levels of those barriers.

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Cite This Study

Alamawi et al. (2025) studied this question.

synapsesocial.com/papers/68c199da9b7b07f3a061b248https://doi.org/10.1155/ecc/6659047
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