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September 10, 2025Clinical Practice and Cases in Emergency Medicine0 citationsOpen Access

The “Unlinkables”: A Case Series of Overcoming Social Determinants of Health for Successful Linkage to Care for HIV from the ED

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PMPhillip MoschellaMGMirinda Ann GormleyKFKiran A. Faryar

Key Points

  • Successful linkage to care for HIV patients was achieved despite challenging social determinants of health.
  • In cases studied, 3 out of 4 patients reached viral suppression, showing effective outcomes from ED programs.
  • Emergency department screening opportunities were utilized to benefit minority patients facing mental health and substance use disorders.
  • Community resources and family support were leveraged to assist patients in navigating barriers to HIV care.

Abstract

Introduction: Despite the success of emergency department (ED)-based universal HIV screening programs in select cities, widespread integration of similar programs across the United States has not followed. Within the US Centers for Disease Control and Prevention (CDC)-designated “Ending the HIV Epidemic (EHE)” areas, ED-based HIV screening is low. This case series highlights successful strategies for notification and linkage to care of patients with various challenging social determinates of health (SDoH). The goal is to inspire more EDs to offer universal HIV screening by providing insight into these challenging SDoH and successful strategies to overcome them. Case Series: We describe four cases, two from a site in upstate South Carolina and two from Cuyahoga County in Ohio, that highlight successful notification and linkage to care of these perceived “worst-case” scenarios. Both ED-based programs are located in CDC-designated EHEareas. We discuss ED screening opportunities and successful linkage for these minority patients (21-36 years of age), and highlight the concomitant and challenging mental health and substance use disorders, and SDoH that were overcome. All four of these patients are currently receiving treatment for HIV and 3 of the 4 have reached viral suppression. Conclusion: Despite challenging SDoH including unstable housing and lack of transportation, phone, and even legal identification documentation, these ED-identified patients with HIV were successfully notified of their disease status and linked to care. The patient navigators used perseverance, connections to local community resources, and leveraged family support toachieve linkage success. The cases serve as both a roadmap and source of inspiration to other EDs in priority EHE areas to begin ED HIV screening programs.

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Cite This Study

Moschella et al. (2025) studied this question.

synapsesocial.com/papers/68c1a12d54b1d3bfb60dc42ahttps://doi.org/10.5811/cpcem.39649
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1P-2054. When Crisis Meets Context: Social Determinants of Health for People Living with HIV Presenting to an Urban Emergency Department2026
  2. 2Challenges to sustained HIV care engagement after ED Re-linkage: The influence of substance use disorders2026
  3. 3Emergency Department Strategies to Identify Out-of-Care People Living With HIV: A Critical Step Toward Ending the HIV Epidemic2025 · 1 citations
  4. 4P-1839. Emergency Department-Based Opt-out Screening and Linkage to Care for Hepatitis C Virus within a Community Healthcare System2026
  5. 5P-264. Beyond Screening: Leveraging Electronic Health Record Data to Identify Out-of-Care People Living With HIV in the Emergency Department2026