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September 10, 2025Cureus0 citationsOpen Access

A Rare Case of Tuberculous Osteomyelitis in a Toddler: Diagnostic Clues and Management Approach

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KPKarthik PrakashRashtreeya Sikshana Samithi TrustAPA PrabhakaranAmes National LaboratoryPIPraveen IyappanIndira Gandhi Medical College and Research Institute

Key Points

  • The diagnosis of tuberculous osteomyelitis was confirmed after a biopsy revealed granulomatous inflammation.
  • Significant improvement in the patient's condition was observed after initiating anti-tubercular therapy.
  • The case illustrates the need for increased awareness of skeletal tuberculosis in areas where it is endemic.
  • Early diagnosis of rare conditions like tuberculous osteomyelitis can prevent serious complications in pediatric patients.

Abstract

Tuberculous osteomyelitis of the proximal tibia is an extremely rare condition in pediatric patients, often presenting as chronic pain, swelling, and nonspecific symptoms that mimic pyogenic osteomyelitis or bone tumors. We report the case of a three-year-old boy who presented with localized swelling and pain in the right proximal tibia for the past 1.5 months. A plain radiograph revealed lytic lesions with marrow involvement, and a biopsy confirmed granulomatous inflammation with caseous necrosis. The patient was diagnosed with tuberculous osteomyelitis and was started on standard anti-tubercular therapy. Significant clinical and radiological improvement was noted on six-monthly follow-up. This case highlights the importance of maintaining a high index of suspicion for skeletal tuberculosis in endemic regions, even in atypical presentations. Early diagnosis and treatment are critical to prevent complications such as growth disturbances, deformities, and joint involvement, ensuring positive outcomes in pediatric patients.

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Cite This Study

Prakash et al. (2025) studied this question.

synapsesocial.com/papers/68c1aab854b1d3bfb60e2cfchttps://doi.org/10.7759/cureus.89235
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A70-36 Tuberculous Osteomyelitis of the Proximal Tibia Mimicking a Bone Tumor in a Young Man: A Diagnostic Challenge2026
  2. 2A Rare Presentation of Osteoarticular Tuberculosis in a Child with Chronic Foot Swelling: A Case Report2026
  3. 3Osteomyelitis Tuberculosis in long bone mimicking bone malignancy: A case report2024 · 1 citations
  4. 4Tubercular osteomyelitis of the distal radius in infancy2026
  5. 5Extrapulmonary forms of tuberculosis. Clinical case report of a child with tuberculous osteoarthritis2024