Orofacial clefts (OFCs), encompassing cleft lip, cleft palate, and cleft lip and palate, represent the most common craniofacial congenital anomalies worldwide. Children with OFCs often experience a variety of oral health challenges, including dental anomalies, malocclusion, early childhood caries, periodontal disease, and altered salivary function. These conditions can significantly impact not only oral function but also speech, nutrition, psychosocial well-being, and overall quality of life. This review synthesizes current literature on the prevalence, etiology, and management of oral conditions associated with OFCs. It highlights the importance of early preventive care, the role of multidisciplinary treatment approaches, and the need to assess oral health-related quality of life (OHRQoL) in affected children. Additionally, the review identifies gaps in current research and underscores the necessity for integrated, evidence-based care strategies tailored to the unique needs of children with OFCs. By drawing attention to these critical areas, this review aims to support clinical decision-making and inform future public health policies focused on improving long-term oral and systemic outcomes for this vulnerable population.
Bin-ying Huang (2025) studied this question.