Increasing interest in functional nutrition has driven the incorporation of probiotics into pet food formulations to enhance digestive health, immune response, and overall well-being in companion animals. This systematic review examines scientific publications, patents, and market developments related to probiotic-enriched pet food from 2014 to 2024. We evaluate major probiotic taxa—including Lactobacillus spp., Bifidobacterium spp., Bacillus spp., and Saccharomyces cerevisiae—based on their resilience during processing, gastrointestinal survival, and documented health benefits. Delivery technologies such as microencapsulation, coating matrices, and post-processing supplementation are analyzed for their effectiveness in preserving probiotic viability within dry and wet food matrices. Patent landscape analysis highlights innovation trends in strain selection, formulation design, and processing methods. In vivo and in vitro studies demonstrate that probiotic supplementation modulates gut microbiota composition, improves fecal parameters, enhances immune markers, and promotes nutrient absorption in both canine and feline models. Market data reveal rapid expansion of commercial probiotic pet food products, yet scientific research remains limited compared to human nutrition. Overall, the findings indicate that while probiotics hold clear potential to improve gastrointestinal health and immunity in pets, evidence remains fragmented, particularly for cats and long-term outcomes. Bridging the gap between industrial innovation and controlled clinical validation will be essential for developing next-generation probiotic pet foods.
Klinmalai et al. (2025) studied this question.
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