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September 28, 2025International Journal of Reproduction Contraception Obstetrics and Gynecology0 citationsOpen Access

Clinicopathological evaluation of abnormal uterine bleeding in peri menopausal women

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SSSaurabh SoniKDK. Pratima DeviLSL. Bimolchandra Singh

Key Points

  • Heavy uterine bleeding is the most common symptom among perimenopausal women, indicating a need for proper assessment.
  • Among 190 cases of abnormal uterine bleeding, 62.1% demonstrated leiomyoma upon histopathological examination of D&C samples.
  • Cross-sectional observations revealed ultrasound was highly effective, achieving 80.5% sensitivity and 100% specificity for diagnosing leiomyomas.
  • This research underlines the prevalence of abnormal uterine bleeding in middle-aged women, with proliferation of leiomyomas being the primary cause.

Abstract

Background: Abnormal uterine bleeding (AUB) is a frequently encountered gynaecological complaint in perimenopausal women and also the most common cause of hysterectomy in their age group. The current study was carried out to evaluate various presentations of perimenopausal Abnormal uterine bleeding and to correlate with histopathological examination of the dilation and curettage (D in adenomyosis, USG is more sensitive (100%) and specific (100%). Clinically, leiomyoma was the most common suspected cause of AUB; radiologically, 50% of leiomyomas and post-hysterectomy histopathological findings showed that 62.1% were leiomyoma, among which 98.9% were proliferative. Only 21% were adenomyosis. The endometrial pattern was 63.7% proliferative, 21.6% secretory, 14.7% disordered proliferative. Conclusions: The abnormal uterine bleeding was common in middle-aged women and heavy bleeding was the common presentation. The proliferative leiomyomas are the major causes for AUB followed by adenomyosis.

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Cite This Study

Soni et al. (2025) studied this question.

synapsesocial.com/papers/68d909fc41e1c178a14f5d92https://doi.org/10.18203/2320-1770.ijrcog20253095
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