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October 2, 2025Clinical Electroencephalography0 citations

Valproic Acid in the Treatment of Epilepsy during the Pediatric Age

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GAGraciela Olmos-Garcla de AlbaJVJorge Malagón Valdez

Key Points

  • Valproic acid showed effective responses in various pediatric epilepsy types, particularly in myoclonic-astatic seizures.
  • Clinical and EEG follow-up over 10 months confirmed the treatment was well tolerated with minimal side effects.
  • Observations indicate that pediatric patients with epilepsy respond sensitively to valproic acid therapy.
  • The study included 85 patients, highlighting significant improvement in juvenile myoclonic epilepsy cases.

Abstract

Summary We studied 85 pediatric patients with different types of epilepsy treated with valproic acid. The clinical and EEG follow-up were performed up to 10 months. Our EEG-clinical observations in this study show that this group of epilepsies during the pediatric age are extremely sensitive to valproic acid with minimal and tolerable side effects. Within a brief period of time an effective response was obtained in the case of epilepsy with myoclonic-astatic seizures juvenile myoclonic epilepsy (impulsive petit mal), classical absence and photosensitive epilepsy.

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Cite This Study

Alba et al. (1986) studied this question.

synapsesocial.com/papers/68de70f583cbc991d0a2371bhttps://doi.org/10.1177/155005948601700106
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